Warner RR1, Schwartz JR, Boissy Y, Dawson TL Jr. (2001) Dandruff has an altered stratum corneum ultrastructure that is improved with zinc pyrithione shampoo. Lodén M , Wessman C. (2000) The antidandruff efficacy of a shampoo containing piroctone olamine and salicylic acid in comparison to that of a zinc pyrithione shampoo. The formula is also SLS free – more great news for sensitive scalps. Instead the cleansing ingredients Sebclair shampoo uses are; Bioderma Node P Apaisant Anti-Dandruff Soothing Shampoo is a fabulous option for sensitive, irritated conditions of mild to moderate dandruff and seborrheic dermatitis. With a combination of 2 anti-dandruff actives and dry flake busting salicylic acid, its overall efficacy is excellent. It washes and smells great and if it weren't for the presence of fragrances and silicones it would be an almost perfect sensitive scalp friendly formulation. Read the entire review

Nizoral contains a 2% dose of antifungal ketoconazole mixed into an 11-ingredient fragrance-free formula. Another go-to shampoo if you suffer from moderate to severe seb derm. Selsun 2.5% shampoo contains a 2.5% concentration of Selenium Sulfide. The 2010 Beiersdorf study found that the combined antifungal shampoo improved ‘wet combing’ on mannequins over a zinc pyrithione shampoo [5]. This easier combing is thought to reduce the need for frequent washing, but this is proposed and not proven. Where can I buy Piroctone Olamine Shampoos?

Piroctone olamine has been used for around 40 years, first developed by Schwarzkopf-Henkel (a subsidiary of Hoechst AG*) for use in anti-dandruff shampoo in the late 1970s. All the initial clinical and safety studies were conducted by Hoechst AG, but this changed in the mid-1990s when other cosmetics companies began using the ingredient [1]. da Rocha Neto AC1, Maraschin M2, Di Piero RM3. (2015) Antifungal activity of salicylic acid against Penicillium expansum and its possible mechanisms of action.

Salicylic Acid is on the other hand used in shampoos, creams, and ointments mainly for its keratolytic effects – the ingredient causes the epidermis to shed more easily, helping to remove dry and flaky skin [17]. You’ll often see salicylic acid referred to as an exfoliator – and it’s added to dandruff shampoos to help shift existing build-up. Piroctone olamine was first submitted for approval to the European Union and United States FDA in the 1980s [2]. The ingredient was first approved for addition to the United States Pharmacopeia (USP) in 2008, after the FDA sought additional safety and effectiveness data in 2004 [3]. More positive results came from a study [6] that compared shampoos containing a combination of piroctone olamine and salicylic acid with coal tar shampoo. The piroctone olamine combination shampoo achieved the largest reduction in Malassezia over an eight-week period. Dry Scalp For some further clarity, Dr. Ben Barankin, told us, “For mild-moderate dandruff, I recommend daily shampooing, and ideally alternating 3 shampoos, each with active anti-dandruff ingredients.” This product is safe for color-treated or chemically processed hair as well as extensions, wigs, and weaves. The main ingredient, sodium chloride (salt), will strip out the keratin in your hair and give you a fresh start.

Where did it come from?

Piroctone olamine works by lowering the levels of lipids on the surface of your scalp which is responsible for making skin cells grow more rapidly than they should. Since there are hundreds of different brands that makes piroctone olamine shampoos, finding the right one for you need might be super challenging. It contains natural ingredients that purify and cleanse the skin without dehydrating it. Its formula with 10% of zinc oxide protects against external aggressions (pollution, sun) while respecting the skin’s natural balance. The ingredients in this product work together to provide you with optimal results.

Schmidt‐Rose, T., Braren, S., Fölster, H., Hillemann, T., Oltrogge, B., Philipp, P., & Fey, S. (2011). ‘Efficacy of a piroctone olamine/climbazol shampoo in comparison with a zinc pyrithione shampoo in subjects with moderate to severe dandruff.’ International journal of cosmetic science, 33(3), 276-282. anti-fungals are best for seborrheic dermatitis e.g. ketoconazole, zinc pyrithione, selenium sulfide, piroctone olamine Nizoral is probably the most effective shampoo on the market to control dandruff caused by seb derm. Oil-free moisturizers are being released in abundance, these won’t feed your seb derm. SebClair appears to get around this problem by adding enough anti-fungal agents to kill the Malassezia as well as feeding them. It’s a bit of a poisoned chalice for the yeast. And it seems to work! It’s all about getting the balance right. But what about the other ingredients. Finding a great anti-dandruff shampoo is tough because almost 99% of the time there’s also known allergens and irritants being used as cleansing agents. What about Sebclair Non-Steroidal Cream? I love it simply because it’s effective and it’s affordable so it’s often my first-line treatment – sometimes in combination with a topical steroid solution..”Slutsky JB , Clark RA , Remedios AA , Klein PA (2010) An evidence-based review of the efficacy of coal tar preparations in the treatment of psoriasis and atopic dermatitis. And on top of this Sebclair uses an ultra-mild, natural preservative system, no essential oils, no fragrance, no parfum and no allergens. Dr. Matthew Zirwas recommended trying a shampoo for, “at least a month because if your old shampoo had ingredients that were causing a dandruff-like rash of their own, it will take 4-8 weeks for that ingredient to work its way out of your body after you start the new stuff.”