Drinking between 3–5 cups of coffee per day or more than 3 cups of tea per day may also reduce the risk of brain diseases such as Alzheimer’s and Parkinson’s by 28–60% ( 10, 11, 12, 13). Caffeine is used for both prevention [34] and treatment [35] of bronchopulmonary dysplasia in premature infants. It may improve weight gain during therapy [36] and reduce the incidence of cerebral palsy as well as reduce language and cognitive delay. [37] [38] On the other hand, subtle long-term side effects are possible. [39] Caffeine is a central nervous system stimulant. It works by stimulating the brain. Caffeine is found naturally in foods and beverages such as coffee, tea, colas, energy and chocolate. Botanical sources of caffeine include kola nuts, guarana, and yerba mate. Caffeine is also available in prescription and non-prescription medications. The easiest way for you to break caffeine dependence is to reduce the amount you’re having gradually. This gives your nervous system time to adapt to functioning without the drug. Children, pregnant women, athletes and caffeine

Toxicity is generally not seen when drinking caffeinated beverages because a very large amount would need to be taken within a few hours to reach a toxic level (10 gm of caffeine is equal to about 100 cups of brewed coffee). Dangerous blood levels are more often seen with overuse of caffeine pills or tablets. [3] Did You Know? Skin protection. Consuming 4 or more cups of caffeinated coffee per day may lower the risk of skin cancer by 20% ( 46, 47).The amount of caffeine in food and drinks varies. For example, an espresso has more caffeine than instant coffee. Similarly, dark chocolate has more caffeine than milk chocolate. Source Grosso G, et al. Coffee, caffeine, and health outcomes: An umbrella review. Annual Review of Nutrition. 2019; doi:10.1146/annurev-nutr-071816-064941.

We are not aware of any safety issues specific to any of the Berocca formulations. The suggested daily intake for Berocca and Berocca Boost is one tablet per day. The suggested daily intake for Berocca Sport is one sachet per day. One review reports that after participants ingested 37.5–450 mg of caffeine, they had improved alertness, short-term recall, and reaction time ( 1). In healthy children, moderate caffeine intake under 400mg produces effects that are "modest and typically innocuous". [74] [75] As early as six months old, infants can metabolize caffeine at the same rate as that of adults. [76] Higher doses of caffeine (>400mg) can cause physiological, psychological and behavioral harm, particularly for children with psychiatric or cardiac conditions. [74] There is no evidence that coffee stunts a child's growth. [77] The American Academy of Pediatrics recommends that caffeine consumption is not appropriate for children and adolescents and should be avoided. [78] This recommendation is based on a clinical report released by American Academy of Pediatrics in 2011 with a review of 45 publications from 1994 to 2011 and includes inputs from various stakeholders (Pediatricians, Committee on nutrition, Canadian Pediatric Society, Centers for Disease Control & Prevention, Food and Drug Administration, Sports Medicine & Fitness committee, National Federations of High School Associations). [78] For children age 12 and under, Health Canada recommends a maximum daily caffeine intake of no more than 2.5 milligrams per kilogram of body weight. Based on average body weights of children, this translates to the following age-based intake limits: [72] Age range A systematic review and meta-analysis from 2014 found that concurrent caffeine and L-theanine use has synergistic psychoactive effects that promote alertness, attention, and task switching; [57] these effects are most pronounced during the first hour post-dose. [57] Physical performance Is drinking tea and coffee bad for my heart? And how much caffeine is too much? BHF dietitian Victoria Taylor says:Extremely high daily intakes of 1,000 mg or more per day have been reported to cause nervousness, jitteriness and similar symptoms in most people, whereas even a moderate intake may lead to similar effects in caffeine-sensitive individuals ( 9, 10). Berocca shouldn’t be given to children because of its high level of caffeine. Caffeine is bad for them. People who are sensitive to caffeine should avoid using berocca, because it contains caffeine. www.berocca.co.uk Berocca Caffeine vs Coffee By default the app starts enabled, and works every 59 seconds. There are some command line switches you can use to alter this behaviour: In contrast, a single Berocca tablet mixed with 8 fluid ounces of water contains 90 mg of caffeine. This means that in terms of caffeine content, Berocca is comparable to an average cup of coffee. However, it’s worth noting that individual variations in caffeine tolerance and sensitivity may affect how you perceive and react to the caffeine in both Berocca and coffee.

Health Canada has not developed advice for adolescents because of insufficient data. However, they suggest that daily caffeine intake for this age group be no more than 2.5mg/kg body weight. This is because the maximum adult caffeine dose may not be appropriate for light-weight adolescents or for younger adolescents who are still growing. The daily dose of 2.5mg/kg body weight would not cause adverse health effects in the majority of adolescent caffeine consumers. This is a conservative suggestion since older and heavier-weight adolescents may be able to consume adult doses of caffeine without experiencing adverse effects. [72] Pregnancy and breastfeeding In a small study, when five healthy adults drank caffeinated water, they experienced a relaxation of the muscle that keeps stomach contents from moving up into the throat — the hallmark of GERD ( 25). Caffeine is broken down mainly in the liver. It can remain in the blood anywhere from 1.5 to 9.5 hours, depending on various factors. [2] Smoking speeds up the breakdown of caffeine, whereas pregnancy and oral contraceptives can slow the breakdown. During the third trimester of pregnancy, caffeine can remain in the body for up to 15 hours. [3] Common causes of rhabdomyolysis include trauma, infection, drug abuse, muscle strain and bites from poisonous snakes or insects. You may not realize that too much caffeine is interfering with your sleep if you underestimate the amount of caffeine you’re taking in.

Gut health. Consuming 3 cups of coffee a day for as few as 3 weeks may increase the amount and activity of beneficial gut bacteria ( 52). Ruxton CHS. The suitability of caffeinated drinks for children: a systematic review of randomised controlled trials, observational studies and expert panel guidelines. Journal of Human Nutrition and Dietetics. 2014;27(4):342-57.

Because caffeine is a drug, if you stop consuming caffeine you may develop withdrawal syndrome. Symptoms usually start a day or two after stopping caffeine. These symptoms can last up to a week, and include: For example, too much caffeine can give you headaches. This is primarily linked to caffeine withdrawal. The blood vessels in your brain become used to caffeine’s effects so if you suddenly stop consuming caffeine, it can cause a headache. Caffeine may cause dizziness. Do not drive or operate machinery, or engage in dangerous tasks until you know how caffeine might affect you. Decreased cancer risk. Drinking 2–4 cups of coffee per day may reduce liver cancer risk by up to 64% and colorectal cancer risk by up to 38% ( 41, 42, 43, 44, 45). One thing to keep in mind is that caffeine may slightly raise blood pressure in some people. However, this effect is generally small (3–4 mmHg) and tends to fade for most individuals when they consume coffee regularly ( 32, 33, 34, 35).

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http://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/caffeine/art-20045678 Avoid large amounts of caffeine-containing foods and beverages, such as coffee, tea, cocoa, cola drinks, energy drinks and chocolate if you are taking higher doses of caffeine tablets. This also includes any herbal, dietary, or prescription medications that contain caffeine. Although coffee and tea are the most concentrated sources of caffeine, it is also found in soda, cocoa, energy drinks and several types of medication.