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Another study found that athletic men taking 3 grams of MSM daily for two weeks had lower levels of IL-6 and less muscle pain after intense resistance exercise ( 11). Summary A 2013 study of 16 unfit men revealed that taking MSM could reduce the signs of oxidative stress on their bodies after exercise, helping to protect against damage caused by free radicals. 12
After exposure to an allergen, many inflammatory substances such as prostaglandins and cytokines are released, which leads to unpleasant symptoms. Gumina S, Passaretti D, Gurzì MD, et al. Arginine L-alpha-ketoglutarate, methylsulfonylmethane, hydrolyzed type I collagen and bromelain in rotator cuff tear repair: a prospective randomized study. Curr Med Res Opin. 2012 Nov;28:1767-74. View abstract. Muscle damage caused by exercise. Research shows that taking MSM daily beginning 10 days before a 14 km running exercise can help reduce muscle damage. A trial published in JMIR Research Protocols in 2018 reported that a daily dose of 3g of MSM could reduce the main symptoms of allergic rhinitis, including a stuffy, runny nose, by more than 50% in just two weeks. 10
Varicose veins and other circulatory problems (chronic venous insufficiency). Research shows that applying MSM and EDTA to the skin can reduce swelling in the calf, ankle, and foot in people with chronic venous insufficiency. But applying MSM alone seems to actually increase swelling. One of the most notable attributes of MSM supplements is that they help accelerate healing and “detox” the body by improving how chemicals enter and leave our cells. MSM essentially makes cells more permeable, releasing certain built-up minerals that can cause problems (like calcium, for example), heavy metals, waste and toxins, while also helping usher in nutrients and water. MSM seems to help the body’s natural free radical-scavenging abilities, which means it lowers oxidative stress as well as the many ailments that come along with it.
O'Dwyer PJ, et al. Use of polar solvents in chemoprevention of 1,2-dimethylhydrazine-induced colon cancer. Cancer 1988;62:944-8. View abstract. Usha PR, Naidu MU. Randomised, Double-Blind, Parallel, Placebo-Controlled Study of Oral Glucosamine, Methylsulfonylmethane and their Combination in Osteoarthritis. Clin Drug Investig. 2004;24(6):353-63. View abstract.
What does Glucosamine cream with MSM do?
This gel is the no-frills, simple and to the point, topical solution. As always, the only use Opti-MSM in this gel because they only use the best. And since it is not mixed with anything, it can be used for just about anything. From the face to the body and the joints, it works well on everything. This may explain why it’s a popular arthritis remedy; a 2004 study of 118 people with osteoarthritis found those taking MSM, glucosamine, or a combination of both, showed a significant improvement in pain and joint swelling compared with those taking a placebo. 6
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